The reference site for Glipizide

Glipizide is an oral rapid- and short-acting anti-diabetic medication from the sulfonylurea class. It is classified as a second-generation sulfonylurea, which means that it undergoes enterohepatic circulation. Second-generation sulfonylureas are both more potent and have shorter half-lives than the first-generation sulfonylureas.

WHAT IS GLIPIZIDE?

Glipizide is used to treat type 2 (noninsulin-dependent) diabetes (formerly ‘adult-onset’), particularly in people whose diabetes cannot be controlled by diet alone.

Glipizide lowers blood sugar by stimulating the pancreas to secrete insulin and helping the body use insulin efficiently. The pancreas must be capable of producing insulin for this medication to work.

However, glipizide is not used to treat type 1 (insulin-dependent) diabetes (formerly ‘juvenile-onset’).

 

Brand Name(s): Glucotrol
CAS nº: 29094-61-9
(glip ih zide)

 

Product Info

The sections below will provide you with more specific information and guidelines related to glipizide and its correct use. Please read them carefully.

FDA Information

This medication, marketed by Pfizer under the brand name Glucotrol®, received final approval from the U.S. Food and Drug Administration in 1984.

Pfizer sells Glucotrol® in doses of 5 and 10 milligrams and Glucotrol XL® (an extended release form of glipizide) in doses of 2.5, 5, and 10 milligrams. Other companies sell generic forms of glipizide, most commonly extended release tablets of 5 and 10 milligrams.

Glipizide is indicated as a dietary adjunct for the control of hyperglycemia.

Why is this medication prescribed?

Glipizide is an oral medium-to-long acting anti-diabetic drug from the sulfonylurea class. It is classified as a second generation Sulfonylurea, which means that it undergoes enterohepatic circulation.

Glipizide is commonly used to treat type 2 (noninsulin-dependent) diabetes (formerly ‘adult-onset’), particularly in people whose diabetes cannot be controlled by diet alone.

Glipizide lowers blood sugar by stimulating the pancreas to secrete insulin and helping the body use insulin efficiently. The pancreas must be capable of producing insulin for this medication to work.

Glipizide is not used to treat type 1 (insulin-dependent) diabetes (formerly ‘juvenile-onset’).

NOTE: approximately 90% of patients with diabetes have type II or non-insulin dependent diabetes mellitus. Type II diabetes usually occurs in adulthood and is associated with obesity and a strong family history of diabetes. The inability to control the blood sugar (glucose) is caused by impaired insulin release by the pancreas and resistance to insulin by cells.

Other uses for this medicine

This medication may sometimes be prescribed for other uses. Please consult your doctor or pharmacist for further information.

Dosage and using this medicine

Glipizide comes in tablets to take by mouth.

It is usually taken once a day, 30 minutes before breakfast.

Take each dose with a full glass of water.

The Glucotrol XL® extended release tablets (glipizide extended release tablets) should be swallowed whole. Do not chew, divide, or crush the tablets.

Take glipizide exactly as directed by your doctor. Do not take more or less of it, or take it more often, than what has been prescribed by your doctor.

What special precautions should I follow?

BEFORE TAKING GLIPIZIDE:

Before taking this medication, please remember to tell your doctor and pharmacist if you are allergic to glipizide or any other drugs.

Inform your doctor and pharmacist what prescription and non-prescription medications you are taking, especially antibiotics, anticoagulants (‘blood thinners’) such as warfarin (Coumadin), dexamethasone (Decadron), diuretics (‘water pills’), estrogens, isoniazid (INH), MAO inhibitors such as phenelzine (Nardil) and tranylcypromine (Parnate), medications for high blood pressure or heart disease, niacin, oral contraceptives, phenytoin (Dilantin), prednisone, probenecid (Benemid), and vitamins.

Tell your doctor if you have or have ever had kidney, liver, heart, or thyroid disease or a severe infection.

Tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. Should you become pregnant while taking glipizide, call your doctor immediately.

If you are having surgery, including dental surgery, tell the doctor or dentist that you are taking glipizide.

Plan to avoid unnecessary or prolonged exposure to sunlight and to wear protective clothing, sunglasses, and sunscreen. Glipizide may make your skin sensitive to sunlight.

What should I do if I forget a dose?

Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose.

Never take a double dose of this medication.

What side effects can this medication cause?

Side effects from glipizide include:

low blood sugar
nausea or vomiting

Tell your doctor if any of these symptoms are severe or do not go away:

dry mouth
upset stomach and vomiting
shortness of breath
breath that smells fruity
decreased consciousness

If you experience any of the following symptoms, call your doctor immediately:

extreme thirst
frequent urination
extreme hunger
weakness
blurred vision
skin rash
itching or redness
exaggerated sunburn
yellowing of the skin or eyes
light-colored stools
dark urine
unusual bleeding or bruising
fever
sore throat

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What storage conditions are needed for this medicine?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

Remember to throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

In case of an emergency/overdose

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

Symptoms of overdose may include:

hunger
nausea
anxiety
cold sweats
weakness
drowsiness
unconsciousness and coma

Product Images

PICTURES OF GLIPIZIDE PILLS

Below you will find images and specific information on the principal types of glipizide that exist, including their respective brand name(s), strength, inscription codes and manufacturers.

The information below includes general information and guidelines for patients taking this medication and should never be used to substitute professional medical advice that can be provided by a qualified physician or family doctor.

Name: GLIPIZIDE
Strength(s): 5 MG
Imprint: WATSON 460
Manufacturer: WATSON LABS.

Name: GLIPIZIDE
Strength(s): 5 MG
Imprint: GG 771
Manufacturer: SANDOZ

Name: GLIPIZIDE
Strength(s): 5 MG
Imprint: 9201
Manufacturer: IVAX PHARMACEUTICALS

Name: GLIPIZIDE
Strength(s): 5 MG
Imprint: MYLAN G1
Manufacturer: MYLAN

Name: GLIPIZIDE
Strength(s): 5 MG
Imprint: GG 771
Manufacturer: GENEVA

Name: GLUCOTROL®
Strength(s): 5 MG
Imprint: PFIZER 411
Manufacturer: PFIZER US PHARM.

Name: GLIPIZIDE
Strength(s): 10 MG
Imprint: WATSON 461
Manufacturer: WATSON LABS.

Name: GLIPIZIDE
Strength(s): 10 MG
Imprint: 9200
Manufacturer: IVAX PHARMACEUTICALS

Name: GLIPIZIDE
Strength(s): 10 MG
Imprint: GG 772
Manufacturer: SANDOZ

Name: GLIPIZIDE
Strength(s): 10 MG
Imprint: MYLAN G2
Manufacturer: MYLAN

Name: GLUCOTROL®
Strength(s): 10 MG
Imprint: PFIZER 412
Manufacturer: PFIZER US PHARM.

 

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